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Texas State University · Mechanical Engineering

Design Integration &
Systems Optimization Lab

Our mission is to advance the design, integration, and optimization of engineering systems through physics-based and data-driven modeling, systems co-design, intelligent decision-making, and interdisciplinary innovation.


"Knowing is not enough; we must apply. Being willing is not enough; we must do." — Leonardo da Vinci (1452–1519)
DISO Lab logo
We are currently hiring graduate students in the Ingram School of Engineering at Texas State University!

Latest updates

News

08 / 2026

Welcome Tanvir Ahmed to the DISO Lab!

We are excited to welcome Tanvir Ahmed to the Design Integration and Systems Optimization (DISO) Lab! Tanvir joined the lab in August 2026 as a Ph.D. student in the Mechanical and Manufacturing Engineering program at Texas State University. For more his info, please see his profile page.

Welcome to the DISO Lab, Tanvir!

08 / 2026

Welcome Dr. Ying-Kuan (Rick) Tsai joins Texas State University and launches the Design Integration and Systems Optimization (DISO) Lab.

Dr. Ying-Kuan (Rick) Tsai has officially joined the Ingram School of Engineering at Texas State University as an Assistant Professor of Mechanical Engineering and launched the Design Integration and Systems Optimization (DISO) Lab.

06 / 2026

Presented our latest work on Bayesian co-design for AM at NAMRC54, State College, PA, USA.

Dr. Tsai presented the paper "UNiCO-AM: Uncertainty-aware Neural Co-design for Additive Manufacturing via an Attention-based Spatio-Temporal Neural Operator and Bayesian Optimization" at the North American Manufacturing Research Conference (NAMRC) 54. This work introduces a co-design framework for additive manufacturing that jointly optimizes material properties and process parameters under uncertainty.

08 / 2025

Received the "Paper of Distinction" at ASME IDETC-CIE Design Automation Conference (DAC).

Top 10 papers selected from 101 accepted papers by the Design Automation Conference (DAC) committee. The recognized paper is "Multi-generational Control Co-Design for Digital Twin-enabled Systems with Deep Reinforcement Learning." Paper of Distinction at ASME IDETC-CIE DAC 2025

06 / 2025

Received the "Outstanding Paper Award" in the Manufacturing Systems Track at North American Manufacturing Research Conference (NAMRC) 53.

Top 2 papers selected from 269 accepted papers by the conference committee. The recognized paper is "Real-Time Decision-Making for Digital Twin in Additive Manufacturing with Model Predictive Control using Time-Series Deep Neural Networks." Outstanding Paper Award at NAMRC 53

The people

Our Team

Dr. Ying-Kuan (Rick) Tsai

Dr. Ying-Kuan (Rick) Tsai

Principal Investigator

Dr. Tsai's research focuses on optimizing dynamic engineering systems, with an emphasis on integrating AI/ML, optimization, modern control, and digital twins. He has published over 20 peer-reviewed papers in the fields of engineering design, optimization, manufacturing, control, and digital twins.

Professional History
- Assistant Professor, Mechanical Engineering, Texas State University, San Marcos, TX, USA (2026–)
- Postdoctoral Scholar, Mechanical Engineering, Northwestern University, Evanston, IL, USA (2024–2026)

Education
- Ph.D. in Mechanical Engineering, Texas A&M University, College Station, TX, USA (2023)
- M.S. in Mechanical Engineering, National Taiwan University, Taipei, Taiwan (2018)
- B.S. in Mechanical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan (2016)

Teaching Interests: Design Optimization, Digital Twins, Dynamics and Control, and Numerical Methods

Tanvir Ahmed

Tanvir Ahmed

Ph.D. Student

Education
- Ph.D. in Mechanical and Manufacturing Engineering, Texas State University, San Marcos, TX, USA (Fall 2025 – Present)
- M.S. in Mechanical and Manufacturing Engineering (2025), Texas State University, San Marcos, TX, USA.

Research Interests: Reinforcement learning-based control co-design, digital twins, embedded sensing and machine learning for physical systems, autonomous and robotic systems, SLAM & Navigation.

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We're hiring

PhD · Master

We welcome applications from candidates with backgrounds in control, design optimization, machine learning, or engineering science.

What we study

Research Areas

We develop fundamental frameworks for optimizing dynamic engineering systems through the integration of artificial intelligence and machine learning (AI/ML), optimization, modern control, co-design, and digital twin technologies. We are building intelligent and adaptable systems that continuously learn from real-world data under uncertainty and evolve over their operational lifecycle with applications to autonomous systems across robotics, advanced manufacturing, automotive, smart materials, and aerospace domains.

AI-Enabled Digital Twins for Real-Time Decision-Making

We develop digital twin frameworks that fuse physics-based models with ML to enable real-time monitoring, control, and uncertainty-aware decision-making throughout a system's lifecycle.

Learn more →

Control Co-Design for Intelligent Autonomous Systems

We advance CCD methodologies that integrate reinforcement learning (RL) and model predictive control (MPC) to jointly optimize physical design and control policies for autonomous systems operating in dynamic and uncertain environments.

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Active Learning and Optimization under Uncertainty

We develop active learning and advanced optimization methods that scale to system-level digital twins with inherent noise for data-efficient and interpretable decision-making across large-scale engineering systems.

Learn more →

Our work

Selected Publications

To see more publications, please go to my Google Scholar.

Google Scholar
Full vehicle active suspension system
Digital Twin 2026

Reinforcement Learning-Based Control Co-Design of Digital Twin-Enabled Full-Vehicle Active Suspension Systems

Ying-Kuan Tsai, Yi-Ping Chen, Vispi Karkaria, Wei Chen

Structural and Multidisciplinary Optimization (Special Issue on Reduced Order Modeling, Generative AI, and SciML in Digital Twins) · April 2026

Digital Twin CCD RL animation
CCD 2026

Digital Twin-Enabled Multi-Generation Control Co-Design with Deep Reinforcement Learning

Ying-Kuan Tsai, Vispi Karkaria, Yi-Ping Chen, Wei Chen

Journal of Mechanical Design · July 2026

(DAC Paper of Distinction at IDETC2025)

Adaptive uncertainty-aware material-process co-design for in-space manufacturing
Optimization 2026

Adaptive Uncertainty Aware Material-Process Co-Design for Sustainable In-Space Manufacturing of Recycled Composites

Ying-Kuan Tsai†, Christian A. Fernandez†, Ryan Daniel Brahan, Anupam Ajit Deshpande, Caleb Isaiah Smith, Yayue Pan, Wei Chen

(†Indicates Equal Contribution)

ASME IDETC-CIE Conference · Houston, Texas · August 2026 (accepted)

Parametric multi-objective CCD
CCD 2026

Parametric Multi-Objective Optimization for Simultaneous and Nested Control Co-Design Formulations with Tube-Based Model Predictive Controllers

Ying-Kuan Tsai, Richard J Malak

Journal of Mechanical Design · April 2026

Uncertainty-aware digital twin concept
Digital Twin 2026

Uncertainty-Aware Digital Twins: Robust Model Predictive Control Using Time-Series Deep Quantile Learning

Yi-Ping Chen, Ying-Kuan Tsai, Vispi Karkaria, Wei Chen

Journal of Mechanical Design · February 2026

MPC additive manufacturing animation
Digital Twin 2026

Real-Time Decision-Making for Digital Twin in Additive Manufacturing with Model Predictive Control Using Time-Series Deep Neural Networks

Yi-Ping Chen, Vispi Karkaria, Ying-Kuan Tsai, Faith Rolark, Daniel Quispe, Robert X Gao, Jian Cao, Wei Chen

Journal of Manufacturing Systems · August 2026

(Manufacturing Systems Outstanding Paper at NAMRC53 in 2025)

Roadmap on AI and ML for smart manufacturing digital twin
Digital Twin 2026

Physics-Based Predictive Control and Real-Time Decision-Making for Digital Twin–Enabled Autonomous Manufacturing

Wei Chen, Vispi Karkaria, Yi-Ping Chen, Ying-Kuan Tsai

In Roadmap on AI and ML for Smart Manufacturing, ed. Jay Lee (Machine Learning: Engineering) · March 2026

Adaptive digital twin of sheet metal forming
Digital Twin 2026

Adaptive Digital Twin of Sheet Metal Forming via Proper Orthogonal Decomposition-Based Koopman Operator with Model Predictive Control

Yi-Ping Chen, Derick Suarez, Ying-Kuan Tsai, Vispi Karkaria, Guanzhong Hu, Zihan Chen, Ping Guo, Jian Cao, Wei Chen

Journal of Manufacturing Systems · June 2026

UNiCO-AM co-design for additive manufacturing
Optimization 2026

UNiCO-AM: Uncertainty-aware Neural Co-design for Additive Manufacturing via an Attention-based Spatio-Temporal Neural Operator and Bayesian Optimization

Vispi Karkaria, Ying-Kuan Tsai, Yi-Ping Chen, Doksoo Lee, Jian Cao, Wei Chen

Manufacturing Letters (accepted) · NAMRC 54, University Park, PA · June 2026

Digital twin framework
Optimization 2025

An Optimization-Centric Review on Integrating Artificial Intelligence and Digital Twin Technologies in Manufacturing

Vispi Karkaria, Ying-Kuan Tsai, Yi-Ping Chen, Wei Chen

Engineering Optimization · January 2025

Stochastic tube-based control co-design
CCD 2025

Control co-design with performance-robustness trade-off using tube-based stochastic model predictive control

Ying-Kuan Tsai, Richard J Malak

ASME Letters in Dynamic Systems and Control (Special Section: Control Co-Design) · July 2025

Bayesian constraint-handling technique for parametric optimization
Optimization 2024

Surrogate‑Assisted Constraint‑Handling Technique for Parametric Multi‑Objective Optimization

Ying-Kuan Tsai, Richard J Malak

Structural and Multidisciplinary Optimization · September 2024

Robust CCD tube-based MPC
CCD 2023

Robust Control Co-Design Using Tube-Based Model Predictive Control

Ying-Kuan Tsai, Richard J Malak

Proceedings of American Control Conference · July 2023

Approximate explicit model predictive controller design
Optimization 2022

Design of approximate explicit model predictive controller using parametric optimization

Ying-Kuan Tsai, Richard J Malak

Journal of Mechanical Design · December 2022

Surrogate modeling for sonic boom minimization in morphing aircraft
Optimization 2022

Surrogate modeling and parametric optimization strategy for minimizing sonic boom in a morphing aircraft

Jonathan Weaver-Rosen, Ying-Kuan Tsai, Justin Schoppe, Yutaka Terada, Richard J Malak, Paul G Cizmas, David S Lazzara

AIAA Scitech 2022 Forum · January 2022

Courses taught

Teaching

ME 4351 Fall 2026

Control Systems

Mechanical Engineering · Texas State University

This course covers introductory concepts of linear control systems.

  • Topics: block diagrams, mathematical modeling of physical systems, the Laplace transform, transfer functions, state-space representation, transient and steady state system responses, and stability.
  • Project: TBD
MEEN 357 Fall 2023

Engineering Analysis for Mechanical Engineers

Undergraduate Course · Mechanical Engineering · Texas A&M University

This course provides a practical foundation for the use of numerical methods to solve engineering problems.

  • Topics: solving systems of linear equations, curve fitting, root finding, numerical integration, numerical differentiation, initial value problems, boundary value problems, eigenvalues, and optimization methods.
  • Project: Apply numerical methods and Python programming to model, simulate, and optimize an autonomous Mars rover capable of navigating challenging Martian terrain.
MEEN 357 Spring 2023

Engineering Analysis for Mechanical Engineers

Undergraduate Course · Mechanical Engineering · Texas A&M University

This course provides a practical foundation for the use of numerical methods to solve engineering problems.

  • Topics: solving systems of linear equations, curve fitting, root finding, numerical integration, numerical differentiation, initial value problems, boundary value problems, eigenvalues, and optimization methods.
  • Project: Apply numerical methods and Python programming to model, simulate, and optimize an autonomous Mars rover capable of navigating challenging Martian terrain.

Join the lab

Openings

We are actively recruiting motivated researchers at multiple levels. If our work excites you, we'd love to hear from you.

PhD

Prospective Ph.D. Students

The Design Integration and Systems Optimization (DISO) Lab is seeking highly motivated Ph.D. students interested in developing fundamental methodologies for the design, control, and optimization of dynamic engineering systems. Our research integrates artificial intelligence and machine learning, optimization, control co-design, modern control, and digital twins, with applications in robotics, advanced manufacturing, automotive systems, smart materials, and aerospace systems.

Students with backgrounds in mechanical engineering, aerospace engineering, robotics, control systems, computer science, applied mathematics, or related fields are encouraged to apply. We value curiosity, creativity, initiative, and a passion for interdisciplinary research.

UG & MS

Undergraduate and Master's Students

Undergraduate and M.S. students at Texas State University who are interested in gaining research experience in AI/ML, optimization, control, digital twins, robotics, manufacturing, autonomous systems, or related areas are encouraged to contact Dr. Tsai.

Please email your resume and a brief description of your interests and research goals. Opportunities may include independent research projects, undergraduate research experiences, and master's thesis or project supervision.

Email Dr. Tsai →

Get in touch

Contact Us

We're always open to collaboration, media inquiries, and prospective student applications.

Location Ingram Hall, Room 4309
601 University Drive
San Marcos, TX 78666
Office hours Mon & Wed 2–4 pm ET